Wrinkle Smoothing Injections

What product is used?

At the Mid Yorkshire Skin Clinic we use a neuromodulator called Botulinum Toxin A. The brands Botox and Azzalure are used. This a purified protein derived from the bacterium Clostridium Botulinum. The medicinal form is manufactured in a stringent and controlled environment and used for medical purposes in very tiny, innocuous amounts.

How do wrinkle smoothing injections work?

Botulinum Toxin A is a neurotoxin which is injected into the muscles to prevent the release of acetylchloline at the neuromuscular juntion. This chemical (acetylcholine) is normally released and passes a chemical message to the muscle to allow it to contract. When this message is blocked the muscle fibres are temporarily paralysed and unable to contract, consequently relaxing the muscle and the skin. As the muscle is unable to contract as much it can prevent wrinkles from forming, improves static wrinkles and prevents existing wrinkles becoming deeper lines/folds.

How popular is this treatment?

Over 61 million vials of Botox® have been distributed during the 25 years of manufacturing. Botox® has been used in the UK for over 10 years. Today, Botox® is the #1 selling product of its kind in the world. Botox® is not tested on animals and supported with more than 12 years of safety and efficiency data.

What areas can be treated?

  • Brow lift
  • Bunny lines on the nose
  • Chin (Dimples/lines)
  • Crow’s feet around the eyes
  • Frown/glabellar lines
  • Forehead lines
  • Gummy smile
  • Marionette lines from the corners of the mouth
  • Masseters/Bruxism (Slim jawline/grinding teeth)
  • Neck lines/lift
  • Nose (to lift downturned nose)
  • Vertical lines around the lips (Perioral)

What happens during my consultation?

Botulinum Toxin A is a prescription only medicine (POM). It is prescribed and administered by a medical professional holding the relevant prescribing qualification ONLY after a face to face consultation/assessment. During your consultation a detailed medical history will be taken, helping the medical specialist to determine whether Botulinum Toxin A is an appropriate medicine for you to receive and whether it will help you achieve the results that you are looking for. This will also reduce the risk of any unwanted side effects from the treatment. During this consultation the potential risks and aftercare recommendations are discussed, helping you determine whether this form of injectable treatment is really right for you.

What happens during my treatment appointment?

step 1


Local anaesthetic topical cream can be applied to the areas to be injected prior to the treatment if necessary, the skin is cleaned and disinfected.

step 2


the Botulinum Toxin A is mixed with a small amount of sodium chloride and injected using a syringe with a tiny needle. The medicine is injected into muscle/just underneath the skin or occasionally intradermally. Some patients describe this as a pinch.

What’s the aftercare advice?

You will be given verbal and written advice. Changes may occur for some people 24 hours after treatment, but this is usually at around 5 days after treatment. A review appointment will be made to check the results between 2-3 weeks after your treatment, in some cases a second treatment is required (this is free of charge).

You will be advised not to touch the treated areas, lay down or do any exercise or heavy cleaning for 4 hours.

How long do the results last?

Around 3-4 months. This can be longer depending on the individual and lifestyle choices.

Who is not suitable for this treatment?

  • Anyone allergic to any of the ingredients in Botulinum Toxin A (Botox or Azzalure). (Botulinum Toxin A, Human Albumin, Sodium Chloride)
  • Skin infection at the injection site
  • Anyone who has disease affecting your muscles and nerves (i.e. Lambert-Eaton Syndrome, Myasthenia Gravis, Lou Gehrig’s disease)
  • If you are pregnant, trying to become pregnant or breast-feeding (It is not known if Botulinum Toxin A can be harmful to your unborn child or if this passes through breast milk, unable to research this)
  • Also tell us if you are taking any medicines including herbal as some may be contraindicated, such as of you have recently had an injection of an intravenous antibiotic or taking muscle relaxants.

Before and after wrinkle smoothing injections

  • Before-Wrinkle smoothing injections - before and after
    After-Wrinkle smoothing injections - before and after
    Before Wrinkle smoothing injections - before and after After

Treatment frequently asked questions (FAQs)

How long does the anti-wrinkle treatment last?
Will I look ‘frozen’ or lack expression?
What are the side effects?
What other conditions is Botox® used to treat?

Book an appointment for your anti-wrinkle treatment now

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